Igual hay algún estudio más por ahí, pero este muestra que para las mRNA 1 sola dosis con gente que ya lo ha pasado sería suficiente (al menos para una temporada). Los efectos adversos más o menos como en la segunda dosis si ya lo has pasado.
AZN MRNA PFE NVAX Esto compartió redplate en IV (final de enero).
"I asked my friend McVest to post a link here to a early release E publication of a prime and boost heterologous approach. In this case it’s adeno virus and mRNA. The data is clearly excellent and the mixed strategy is simply better. Now companies will resist this but it’s coming. I assure you it’s coming. Now historically prime with adeno boost with protein subunit was the best result in HIV studies. I can assure you that that will be true for CoViD. I can assure you that public health folks are now looking hard at the booster market and that includes boosting with novel strains. In the weeks ahead everything will begin to shift to how we do boosters and what combo sequences give us the best chances against these new strains.
I have no doubt that prime and boost with different vaccines is the right direction. Many previous studies have already proven this when 2 different platforms are used, the results is much better."
