Curiosa lista que lleva meses ya en el foro de Yahoo, que se va actualizando cada vez que sucede un evento. Del forero usano "bballgm"
Bucket List Update
1) Starting RSV Maternal in pregnant women Phase IIb trial (antibody transfer) - CHECK
2) Good Pandemic H7N9 flu w/ Matrix-M phase I/II trial top line data for adult - CHECK
3) BARDA picks up 2nd half of contract worth ~$70MM - CHECK
4) Starting RSV Elderly Phase IIa trial (no adjuvants) - CHECK
5) Fast Track for H7N9 w/ Matrix-M - CHECK
6) Collection of $3MM from seasonal flu IND
7) Starting of Quad Seasonal Flu phase IIb trial in young adults
8) Starting RSV Pediatrics Phase I trial - CHECK
9) Positive Non-Human Primate Ebola Preclinical Results
10) Starting Ebola Phase I trial
11) Starting RSV/Flu combo "Respiratory Vaccine" Phase I trial
12) Good Quad Seasonal Flu phase IIb trial top line data in young adults
13) Good top line Phase IIb results for RSV Maternal in pregnant women
------------------------------------Jackpot Scenarios
*) Stockpile Order for H7N9 w/ Matrix-M
*) Stockpile or EUA Order for Ebola w/ Matrix-M
*) Stockpile or Saudi Order for MERS
*) Possible new BARDA contract or NIH/WHO funding for MERS/H5N1/Ebola
------------------------------------Nice to haves
*) Any trial improvements in India (Rabies, trivalent flu, malaria, etc.) - "CHECK" - flu in Phase III and Rabies with positive results
*) Matrix-M used in third party vaccines
The updates to the Bucket List is happening almost too often with these checks happening so close together. I'm glad that Novavax prioritized the RSV Pediatrics ahead of the seasonal flu vaccine. The RSV program is the crown jewel and future of NVAX, we need to accelerate it as much as possible. RSV Elderly was the most important. Now, all of the attention can be focused on seasonal flu vaccine. It is moving beautifully clinically, and firing on all cylinders. All of this work will pay off handsomely when the results come rolling in. I think the Ebola program will be the big question mark for Novavax in the clinic as no one really knows if it really works. Let's go Novavax! NVAX