Re: Farmas USA
PSTI
La mentan en un artículo de farma como proveedora de células fabricads en biorreactor. Igual no hay que soltarla.
Why 3D and why bioreactors? Adherent cells need a surface to grow on, the more surface you have, the more cells you can produce. 3D culture of cells, whether in scaffolds or in cell aggregates, allows for a multifold increase in the efficiency of cell culture. The more surface area, the more cells can be cultured in a given volume.
At present, very few cell therapy companies are pursuing the 3D cell culture strategy. Taking Pluristem Therapeutics as an example, one 5-liter packed bed bioreactor with 3D scaffold (FibraCel) yields a number of cells equivalent to approximately 70 2D 10-layer "cell factory" flasks. This represents a 3D advantage in efficiency of cells produced per volume of more than 70-fold.
http://www.pharmaevolution.com/author.asp?doc_id=560363§ion_id=3105
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