España
Joder que cabrones, 100 shares ....
Les costo el viernes en sesion tirarla 10 centavos y como aprovechan en pre para con nada bajarla otro tanto.
De todas maneras, si la bajan pero no acompaña ningun volumen mas ... ya me direis que adelantan.
En fin, quedan 2h para apertura .
CLSN
el unico comentario en stocktwits al respecto
Demanda a CLSN
Lo divertido es que demanden a CLSN basándose en el artículo de Seeking. ¿No podrían hacer precisamente lo contrario?
http://finance.yahoo.com/news/rosen-law-firm-announces-investigation-051600366.html
«Después de nada, o después de todo/ supe que todo no era más que nada.»
deporte nacional esto de las investigaciones a farmas.
investigaciones "en defensa de los inversores" que luego acaban en nada ...
estos americanos carroñeros ...
al de seeking no le dicen nada porque no tiene un puto duro, ja,ja!
lo que pasa,mes que haciendo esto contra CLSN dan mas credibilidad al de seeking ...
en fin, lo bueno de estar pillado en un valor es que no hay decisiones que tomar , solo la voluntad de aguantar.
CLSN
Pero sabes porque se repliegan?
porque llega Julio, llega el verano, llega el fin del primer semestre, llega la hora de tomar beneficios, de que salga el dinero, de la baja actividad ... del aburrido verano ( a juzgar por como fue el año pasado )
me plantee estar al maximo de liquidez para el 1 de Julio y lo que estoy es al maximo de comprometido ... je,je ...
¿Pero con anillo y todo?
«Después de nada, o después de todo/ supe que todo no era más que nada.»
EXHIBIT INDEX
Exhibit No. Description
99.1 Press Release titled, “ARRAY BIOPHARMA ANNOUNCES POSITIVE INTERIM RESULTS FROM COMBINATION TRIAL OF ARRY-520 WITH KYPROLIS AT THE 2013 EUROPEAN HEMATOLOGY ASSOCIATION CONGRESS”
Array BioPharma Announces Positive Interim Results From Combination Trial Of ARRY-520 With Kyprolis At The 2013 European Hematology Association Congress
BOULDER, Colo., June 17, 2013 /PRNewswire/ -- Array BioPharma Inc. (NASDAQ: ARRY) today announced that interim results from an ongoing ARRY-520 clinical trial in multiple myeloma (MM) were presented at the 2013 Congress of the European Hematology Association in Stockholm, Sweden. Also at the meeting, Array presented updated information on a potential patient selection marker for ARRY-520. ARRY-520 is a highly selective, targeted inhibitor of KSP with a mechanism of action distinct from other drugs used to treat MM that continues to advance in clinical trials.
(Logo: http://photos.prnewswire.com/prnh/20121029/LA02195LOGO)
Phase 1 Study of the Novel KSP Inhibitor ARRY-520 + Carfilzomib in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM) (Protocol # ARRAY-520-112)
Interim data from an ongoing combination trial of ARRY-520 with Kyprolis® (carfilozomib) in patients with relapsed or refractory MM who are refractory or intolerant to Velcade® (bortezomib) were reported. The combination has demonstrated early signals of activity with a disease control rate (complete response, partial response, minimal response or stable disease) of 82% and a clinical benefit rate (≥minimal response) of 53%, including one complete response. In addition, the combination has been well tolerated with no unexpected hematologic toxicity and a manageable side effect profile. More than half of the patients enrolled remain on study, with patients in the current cohort receiving full doses of both drugs without reaching a maximum tolerated dose (MTD).
"To date, the combination of ARRY-520 with Kyprolis has been well tolerated. Reversible neutropenia is the most common adverse event and does not appear to be additive relative to the observed events for either drug alone," said Jatin J. Shah, M.D., Assistant Professor, Lymphoma/Myeloma, Division of Cancer Medicine, The University of Texas, MD Anderson Cancer Center. "While this is an ongoing study, and we await mature data, there have been promising signs of activity in a heavily pretreated population, which includes several patients previously exposed to ARRY-520 or carfilzomib."
Alpha 1-Acid Glycoprotein (AAG) is a Potential Patient Selection Marker for Clinical Activity of ARRY-520 in Relapsed and Refractory Multiple Myeloma (MM) (Protocol # ARRAY-520-212)
Data on a potential patient selection marker was also presented from multiple studies of ARRY-520 in patients with relapsed and refractory multiple myeloma. To date all responses have occurred in patients with low levels of alpha-1-acid glycoprotein (AAG) and these patients had longer event free survival (time to next treatment or death). In a single-agent Phase 2 ARRY-520 clinical study, the median overall survival was reported to be markedly longer in patients with low AAG as compared to patients with high AAG (20.2 vs. 4.5 months). These results may enable more precise targeting of patient populations who will benefit from ARRY-520.
About ARRY-520 for Multiple Myeloma
ARRY-520 is a highly selective, targeted inhibitor of KSP with a novel mechanism of action distinct from currently approved drugs to treat multiple myeloma (MM). ARRY-520 preferentially acts on MM cells, versus terminally differentiated or epithelial cells, based on Mcl-1 survival dependence. As predicted by its targeted mechanism, no treatment-related neuropathy and minimal non-hematologic adverse events, including gastro-intestinal and dermatological toxicities, have been reported with ARRY-520 therapy at the recommended dose.
ARRY-520 is currently advancing in three clinical trials. Data from these three active trials will inform our pivotal trial decisions:
Phase 2 trial in combination with dexamethasone in patients with MM refractory to Revlimid® (lenalidomide), Velcade® (bortezomib) and dexamethasone therapy.
Dose escalation trial in combination with Velcade® plus dexamethasone in patients with relapsed or refractory MM.
Investigator-sponsored dose escalation trial in combination with Kyprolis® (carfilzomib) in patients with relapsed or refractory MM who are refractory or intolerant to Velcade® therapy.
ARRY
Pues fuera coñas, tambien, je,je...
