Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors (Fase 1/2)
Estimated Enrollment:90
Study Start Date:August 2008
Estimated Study Completion Date:July 2012
Estimated Primary Completion Date:July 2012 (Final data collection date for primary outcome measure)
Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery (Fase 1/2)
Estimated Enrollment:48
Study Start Date:May 2012
Estimated Primary Completion Date:January 2014 (Final data collection date for primary outcome measure)
Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias (Fase 1)
Estimated Enrollment:40
Study Start Date:June 2010
Estimated Study Completion Date:June 2013
Estimated Primary Completion Date:June 2013 (Final data collection date for primary outcome measure)
Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors (TH-CR-410) (Fase 1)
Estimated Enrollment:58
Study Start Date:June 2011
Estimated Study Completion Date:June 2013
Estimated Primary Completion Date:June 2013 (Final data collection date for primary outcome measure)
Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib in Subjects With Relapsed/Refractory Multiple Myeloma (Fase 1/2)
estimated Enrollment:60
Study Start Date:February 2012
Estimated Study Completion Date:January 2014
Estimated Primary Completion Date:January 2014 (Final data collection date for primary outcome measure)